AUXOFERM® Saccharomyces boulardii is a probiotic yeast and used in the treatment of specific gut and digestive diseases. It is resistant to most antibiotics and also much more acid-resistant and, therefore, better able to survive the passage through the gastrointestinal tract. It is beneficial to use it in combination with probiotic bacteria as it has a different mode of action. This probiotic yeast has the ability to bind pathogenic bacteria and epithelia receptors, thereby blocking the pathogen adherence to the epithelia, and it helps to maintain the epithelia barrier integrity.
This is a unique feature that differs from other probiotic microorganisms. Through binding to the epithelia receptor of the host, S. boulardii also modulates the host cell innate and adaptive immune system to counteract pro-inflammatory responses. Furthermore, S. boulardii improves the consumption of nutrients by stimulating the release of digestive enzymes.
Saccharomyces boulardii is the best known probiotic yeast and the only registered probiotic eukaryotic microorganism. The organism was discovered in 1920 by Henri Boulard in Indochina and the commercial use of this yeast for diarrhoea treatment was introduced in the early 1950s. In contrast to probiotic bacteria, this probiotic yeast is less well known and its application has, so far, been focused on the treatment of specific gut and digestive diseases.
Key Features and Benefits
- Recommended by the World Gastroenterology Organization for the treatment of diarrhoea
- Survives passage to the gastrointestinal tract
- Can be used in combination with an antibiotic treatment
- Binds pathogens
- Prevents the binding of pathogens to epithelial receptors
- Improves the consumption of nutrients
- Activates the host’s innate and adaptive immune system