Nucleotides are semi-essential nutrients whose availability is growth limiting under certain conditions.

Nucleotides play a major role in almost every biological process. For instance, they are building blocks for DNA and RNA, and carriers of metabolic energy (i.e. ATP). Nucleotides are semi-essential nutrients: under conditions of rapid growth, stress and disease the own de novo synthesis capacity of animals is not sufficient. Supplementation of animal feed with nucleotides improves animal productivity with respect to average daily gain and feed conversion ratio. This  effect  is  especially  pronounced  in  the  first  weeks  after  weaning,  also  resulting  in  a reduction of diarrhea. Moreover, nucleotides are known to enhance the immune system. Consequently, dietary nucleotides provide a valuable tool to the livestock producer.