Yeast beta-glucan for immune support

High quality yeast beta-glucan with high degree of branching to naturally stimulate the immune system*.

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NEIVA® Glucan Max - Beta-glucan for immune support

The specific beta-1,3/1,6 linkage of glucose units in NEIVA® Glucan Max is known to be particularly effective at stimulating the immune system through two different receptors. NEIVA® Glucan Max's mode of action is substantiated by comprehensive scientific studies.

Key function of NEIVA® Glucan Max

NEIVA® Glucan Max supports and stimulates the immune system* by:

  • activating prime key immune cells such as macrophages, monocytes and neutrophils
  • stimulating the production of cytokines
  • enhancing the effectiveness of vaccines

Benefits of NEIVA® Glucan Max

  • High levels of beta-glucan: 75% ±1%
  • More branching than other beta-glucan products made from yeast, oat or barley
  • Free from artificial additives and preservatives with no synthetic ingredients 

NEIVA® Glucan Max Application

NEIVA® Glucan Max can be formulated in various dosage forms and has many applications such as functional food, sports nutrition and dietary supplements.

NEIVA® Glucan Max can be mixed into dry matrices, powder blends, pastes or emulsions. Being insoluble, it can be dispersed into liquids or lipids through high shear mixing. Our yeast beta-glucan is subjected to a gentle purification and drying process resulting in a narrow particle size distribution for convenient handling.

What is yeast beta-glucan?

Yeast beta-glucans are polysaccharides found in the cell walls of Saccharomyces cerevisiae, commonly known as baker’s yeast. These compounds consist of glucose molecules linked together in a specific branched structure. This unique molecular structure plays a crucial role in their functionality and biological activity.  

1. Immune System Modulation

Yeast beta-glucans are known for their profound impact on immune function. They stimulate various parts of the immune system, enhancing the body’s ability to defend against pathogens and infections. When interacting with specific receptors on immune cells, such as Dectin-1, they trigger a sequence of events that produces immune mediators and activates immune responses.1

2. Cardiovascular Health Support

Yeast beta-glucans may contribute to cardiovascular health by lowering cholesterol levels. Additionally, they offer potential benefits in managing blood sugar levels and supporting digestive function.2

3. Antioxidant Properties

The antioxidant properties of yeast beta-glucans can help combat oxidative stress and reduce inflammation in the body, contributing to overall well-being.3

In summary, yeast beta-glucans are multifaceted bioactive compounds with significant benefits for immune function, cardiovascular health, and overall wellness.

 

Yeast beta-glucan mechanism for immune stimulation

Download our latest whitepapers below to learn more about what makes yeast beta-glucan particularly effective for immune support.

NEIVA® Glucan Max: Structural Advantages for Enhanced Immunomodulation

NEIVA® Glucan Max is a highly effective yeast-derived beta-glucan that offers superior immune support. Its unique branching pattern and insoluble, high molecular weight structure ensure efficient interaction with immune cells, enhancing immunomodulatory activity. Produced using a proprietary solvent-free process, NEIVA® Glucan Max’s beta-glucan structural integrity is preserved, optimising its immune health benefits.

NEIVA® Glucan Max: What is the Difference between Yeast and Cereal Beta-Glucan?

Beta-glucans are a group of naturally occurring polysaccharides found in the cell walls of bacteria, fungi, yeast, algae, and cereals. However, not all glucans are created equal. Both cereal and yeast beta-glucans are widely known and extensively used for their health benefits, which can be broadly categorized into immune-stimulation and metabolic health improvement1. We compare these health heroes and outline the key differences. 

Mode of action

NEIVA® Glucan Max stimulates phagocytic activity

We have evaluated the effects of NEIVA® Glucan Max on the phagocytic activity of monocytes, neutrophils and peritoneal macrophages and shown significant stimulation in all three cases. Additionally, our data shows that NEIVA® Glucan Max has significant biological activity and stimulates both cellular and humoral immune responses.4 

Phagocytic Activity*

* Normalized data

Phagocytic activity refers to the ability of specialized cells, known as phagocytes, to ingest and sometimes digest foreign particles, including pathogenic bacteria. These immune cells—such as macrophages, neutrophils, and monocytes—play a crucial role in our body’s defence against infections.

Yeast beta-glucans are known for their immunomodulatory properties. When beta-glucans bind to specific receptors on phagocytes, they promote phagocytosis and the release of cytokines. This activation results in a cascade in the immune response, making beta-glucans essential contributors to our body’s defence mechanisms.

Why choose NEIVA® by Ohly for your immune support applications?

We've been creating high-quality, reliable yeast products for almost 200 years. Throughout that time, we’ve never compromised on quality, meaning you can expect great results from our products, time and again. We have exacting quality control and assurance processes in place to make sure of it.

We’re always looking for new ways to improve our products and create new ones. Our products are developed by a team of yeast experts who can work with you to find the right solution for your next innovation. Our range of products is constantly expanding, thanks to our investment in intensive research and development.

But we’re also committed to playing an active role in addressing sustainability challenges across three pillars - people, customers and planet.

References:

  1. Auinger et al. (2013). European Journal of Nutrition, 52(8), 1913-1918 : https://pubmed.ncbi.nlm.nih.gov/23340963/
  2. Zabriskie et al. (2020). Nutrients, 12(4), 1144 β: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770584/
  3. Utama et al. (2020) Systemic reviews in Pharmacy , 11 (10), 868-873: https://www.mdpi.com/2072-6643/12/4/1144
  4. Ohly data 2023

This page is intended to provide information about Ohly's ingredients, used in various food/dietary supplement products around the world. It is only intended for business to business and to provide information to food/dietary supplement professionals and is not designed for the general public. Statements used on this website have not been evaluated by the Food and Drug Administration or any other competent authority. Products are not intended to diagnose, treat, cure or prevent any disease.